کوکوات پلی اتیلن گلیکول 7 گلیسرول
| CAS number | 67701-33-1 |
| HS Code | 29157030 |
| Storage | Storage at 5 to 30 °C |
| SDS | available |
| Appearance | Conforms | ||
| Solubility | Conforms | ||
| Relative density | ~ | 1.05 | |
| Alkalinity | ≤ | 0.5 | |
| Saponification value | 85.0 to 105.0 | ml | |
| Hydroxyl value | 170.0 to 210.0 | ||
| Acid value | ≤ | 5.0 | % |
| Iodine value | ≤ | 5.0 | % |
| Limit of ethylene oxide | ≤ | 0.0001 | % |
| Limit of dioxane | ≤ | 0.0010 | % |
| Total ash | ≤ | 0.5 | % |
| Water | ≤ | 1.0 | % |
Polyethylene Glycol 7 Glyceryl Cocoate (PEG-7 Glyceryl Cocoate) is a non-ionic surfactant and emulsifier derived from the esterification of glycerol with fatty acids from coconut oil, followed by ethoxylation. It appears as a clear to pale yellow, odorless or nearly odorless liquid and is widely used in pharmaceutical and laboratory formulations for its emulsifying, solubilizing, and stabilizing properties.
🏭⚗️ Production
PEG-7 Glyceryl Cocoate is synthesized through the esterification of glycerol with caprylic and capric acids (C8 and C10 fatty acids) derived from coconut oil, followed by ethoxylation with ethylene oxide. This process yields a mixture of polyethylene glycol esters that are liquid at room temperature, making them suitable for various pharmaceutical and laboratory applications.
🔬 Properties
PEG-7 Glyceryl Cocoate has a molecular weight of approximately 600 g/mol. It is soluble in both water and oil, has a low viscosity, and is chemically stable. The substance exhibits excellent emulsifying and solubilizing properties, making it effective in enhancing the bioavailability of poorly soluble drugs and active ingredients. It also acts as a stabilizer in emulsions and can function as a co-emulsifier in oil-in-water systems.
🧪 Applications
In pharmaceutical formulations, PEG-7 Glyceryl Cocoate serves as a carrier for fat-soluble vitamins (A, D, E, K), herbal extracts, and sensitive active pharmaceutical ingredients (APIs). It is used in oral formulations such as softgel capsules, syrups, and dietary supplements. Additionally, it is employed in topical applications like creams, ointments, and gels, and can be used in certain injectable formulations.
In laboratory settings, PEG-7 Glyceryl Cocoate is utilized as a solubilizing agent to improve the dissolution of hydrophobic compounds in aqueous solutions. It also serves as a stabilizer in emulsions and as a carrier in drug delivery systems.
⚠️ Safety
PEG-7 Glyceryl Cocoate is generally recognized as safe for topical and oral use in recommended concentrations. It is non-toxic, non-irritating, and hypoallergenic for most individuals. However, rare allergic reactions may occur in individuals sensitive to coconut or palm-derived products. Standard handling procedures, including proper storage and hygiene, should be followed to ensure safety during pharmaceutical or laboratory use.
