پایپریدین برای سنتز

Piperidine is a colorless to pale yellow liquid organic compound with a strong ammoniacal odor, widely used as a building block and reagent in organic synthesis, especially in pharmaceutical and chemical laboratories.

🏭⚗️ Production
Piperidine is commonly produced by hydrogenation of pyridine or via ring-closure reactions from appropriate precursors. For synthesis purposes, it is purified to high purity grades and often supplied as an anhydrous or stabilized solution.

🔬 Properties
Its chemical formula is C₅H₁₁N with a molar mass of 85.15 g/mol. Piperidine is a cyclic secondary amine, miscible with many organic solvents and moderately soluble in water. It is a volatile liquid with a boiling point around 106 °C and acts as a strong base and nucleophile.

🧪 Applications
Piperidine is extensively used in organic synthesis as a catalyst, base, and nucleophilic reagent for producing pharmaceuticals, agrochemicals, and dyes. It is involved in the synthesis of alkaloids, heterocycles, and as a precursor in medicinal chemistry. In laboratories, it facilitates substitution, condensation, and polymerization reactions.

⚠️ Safety
Piperidine is flammable, toxic, and has a strong, unpleasant odor. It can cause irritation to skin, eyes, and respiratory system. Proper handling requires gloves, goggles, and working under a fume hood. It should be stored in tightly sealed containers away from heat, sparks, and oxidizing agents.