معرف دراگندورف

Dragendorff’s Reagent is a chemical reagent widely used for the detection of alkaloids in plant extracts and pharmaceutical samples through precipitation reactions.

🏭⚗️ Production
Dragendorff’s reagent is prepared by mixing bismuth subnitrate dissolved in acetic acid with potassium iodide (KI) solution. The reagent is typically freshly prepared by combining these two solutions to form a clear, orange to reddish-brown solution containing bismuth-iodide complexes.

🔬 Properties
Dragendorff’s reagent appears as a clear orange or reddish-brown solution. It reacts with alkaloids to produce orange or reddish precipitates, allowing qualitative and quantitative analysis of alkaloid content. The reagent is sensitive and specific for alkaloids, making it a standard tool in phytochemistry.

🧪 Applications
Dragendorff’s reagent is extensively used in phytochemical screening to detect the presence of alkaloids in plant extracts. It is also used in pharmaceutical quality control and forensic analysis to identify alkaloid substances. The formation of a colored precipitate confirms the presence of alkaloids.

⚠️ Safety
Dragendorff’s reagent contains bismuth and iodine compounds, which can be irritating or harmful if ingested or upon skin contact. Use gloves and eye protection when handling. Work in a well-ventilated area and avoid inhalation of vapors. Store in a tightly closed container away from light and incompatible chemicals.