دی کلرومتان HPLC
| Formula: | CH2Cl2 |
| Density: | 1.33 g/cm3 (20 °C) |
| Molar mass: | 84.93 g/mol |
| CAS number: | 75-09-2 |
| EC index number: | 602-004-00-3 |
| HS code: | 29031200 |
| EC number: | 200-838-9 |
| Storage (temperature): | Store at +15°C to +25 °C |
| SDS | available |
| RTECS: | PA8050000 |
| R phrase: | R 40 |
| S phrase: | S 23.2-24/25-36/37 |
| Odour: | seweetish |
| Form: | liquid |
| Color: | colourless |
| Explosion limit: | 13 -22 Vol % |
| Ignition temperature: | 605 °C |
| Solubility in water: | 20 g/l (20 °C) |
| Boiling point: | 40 °C (1013 hPa) |
| Melting point: | -95 °C |
| Vapour pressure: | 475 hPa (20 °C) |
| Evaporation number: | 1.9 °C |
| Thermal decomposition: | > 120 °C |
| Viscosity dynamical: | 0.43 mPa*s (20 °C) |
| Saturation concentration: | 1549 g/m3 (20 °C) |
| Assay | ≥ | 99.9 | % |
| Solubility | Conforms | ||
| Description | Conforms | ||
| Identification | Conforms | ||
| Specific gravity | 1.318– 1.322 | g/cm3 | |
| Residue on evaporation | ≤ | 5.0 | mg/l |
| Acidity & Alkalinity | ≤ | 0.0002 | meq/g |
| Transmission at 240nm | ≥ | 70 | % |
| Transmission at 254nm | ≥ | 90 | % |
| Transmission from 260nm | ≥ | 99 | % |
| Water | ≤ | 0.01 | % |
| Filtered by 0.2 μm suitable filter |
Dichloromethane for HPLC is a high-purity, analytical-grade chlorinated solvent widely used in chromatographic, analytical, and sample-preparation workflows requiring low UV absorbance and minimal chemical impurities.
🏭⚗️ Production
Purified through controlled distillation, multi-stage filtration, and rigorous removal of stabilizer residues, water, and volatile impurities. Quality-controlled to meet HPLC-grade specifications with extremely low levels of non-volatile matter and UV-absorbing contaminants. Packaged in airtight, chemically resistant containers designed to minimize evaporation, oxidative degradation, or contamination during storage and handling.
🔬 Properties
A clear, colorless, highly volatile liquid with a mild, sweet odor. Poorly miscible with water but freely miscible with most organic solvents. Exhibits strong solvency power, low UV absorbance, and moderate polarity, making it suitable for normal-phase chromatography. Chemically stable under recommended conditions but may degrade in the presence of strong bases or high temperatures. Store in a cool, dry, well-ventilated area away from heat sources, in tightly sealed, compatible containers (typically amber or opaque to reduce photodegradation).
🧪 Applications
Used in normal-phase HPLC for separation of hydrophobic, lipophilic, and neutral analytes requiring strong elution power. Commonly applied in method development, extraction procedures, sample cleanup, and preparation of standard solutions where high purity and low background signal are essential. Frequently employed in solvent partitioning workflows and analytical methods involving complex organic samples due to its strong dissolving capability and reproducibility in chromatographic systems.
⚠️ Safety
Volatile, harmful, and potentially carcinogenic with risks upon inhalation, skin contact, or ingestion. Vapors may cause dizziness, CNS effects, and respiratory irritation; prolonged exposure can lead to liver or kidney damage. Contact may cause skin dryness or irritation. Use only in well-ventilated environments or fume hoods. Wear appropriate PPE including gloves resistant to chlorinated solvents, goggles, and lab coat. Keep away from heat, flames, and incompatible materials such as strong bases and reactive metals. Store in tightly closed containers and follow all institutional safety guidelines when handling chlorinated solvents.
