Disodium hydrogen phosphate (Na₂HPO₄), HPLC grade, is a highly purified inorganic salt used primarily in high-performance liquid chromatography (HPLC) as a buffering agent. It appears as a white, water-soluble crystalline powder.
🏭⚗️ Synthesis
It is synthesized by neutralizing phosphoric acid (H₃PO₄) with sodium hydroxide (NaOH) or sodium carbonate (Na₂CO₃) under controlled pH conditions. The resulting solution is purified and crystallized to HPLC-grade quality.
🧪 Applications
• Preparation of accurate buffer solutions for HPLC analysis
• Used in pharmaceutical and food quality control
• Suitable for use in advanced laboratory and research settings
⚠️ Hazards
May cause eye, skin, and respiratory irritation. Use appropriate personal protective equipment and follow lab safety guidelines.
