دایمتیکون350
| Molar mass | 7631-86-9 |
| CAS number | 39100090 |
| HS Code | Storage at 5 to 30 °C |
| Storage | available |
| SDS |
| Appearance | Conforms | ||
| Identification | Conforms | ||
| Solubility | Conforms | ||
| Specific gravity | 0.965 to 0.973 | ||
| Viscosity | 332.5 to 367.5 | Cs | |
| Refractive index | 1.4013 to 1.4053 | ||
| Loss on heating | ≤ | 0.3 | % |
| Heavy metals | ≤ | 0.0005 | % |
| Acidity | ≤ | 0.1 | ml |
| Assay (nominal viscosity) | 332.5 to 367.5 | Cs |
Dimethicone 350 is a medium-viscosity silicone fluid with a viscosity of approximately 350 centistokes. It is widely used in pharmaceutical and laboratory settings due to its unique properties and versatility.
🏭⚗️ Production
Dimethicone 350 is synthesized through the polymerization of dimethylsiloxane monomers under controlled conditions. The resulting polymer is purified to meet the required standards for pharmaceutical and laboratory use. It is typically available as a colorless, odorless liquid with a smooth, non-greasy texture.
🔬 Properties
Dimethicone 350 exhibits low surface tension, high spreading coefficient, and excellent thermal stability. It is chemically inert, non-toxic, and resistant to oxidation, making it suitable for various applications. The compound is hydrophobic, forming a protective barrier on surfaces, and has a high permeability to gases, allowing for the respiration of the skin.
🧪 Applications
In pharmaceuticals, Dimethicone 350 is used as an anti-foaming agent in oral suspensions, syrups, and topical creams. Its ability to reduce surface tension helps prevent the formation of foam during manufacturing processes, ensuring accurate dosing and product consistency. Additionally, its lubricating properties make it useful in tablet coatings and ointments, enhancing ease of application and patient comfort.
In laboratory settings, Dimethicone 350 serves as a lubricant for equipment, a mold release agent, and a component in microfluidic devices. Its chemical inertness and stability under varying conditions make it ideal for these applications.
⚠️ Safety
Dimethicone 350 is generally considered safe for use in pharmaceutical and laboratory applications when used within recommended concentrations. However, it can be a mild irritant to the skin and eyes. Prolonged or excessive exposure may lead to adverse effects. Therefore, appropriate safety measures, including the use of personal protective equipment and proper ventilation, should be observed when handling Dimethicone 350.





