دایمتیکون1000
| Molar mass | 7631-86-9 |
| CAS number | 39100090 |
| HS Code | Storage at 5 to 30 °C |
| Storage | available |
| SDS |
| Appearance | Conforms | ||
| Identification | Conforms | ||
| Solubility | Conforms | ||
| Specific gravity | 0.967 to 0.975 | ||
| Viscosity | 950.0 to 1050.0 | Cs | |
| Refractive index | 1.4013 to 1.4053 | ||
| Loss on heating | ≤ | 0.3 | % |
| Heavy metals | ≤ | 0.0005 | % |
| Acidity | ≤ | 0.1 | ml |
| Assay (nominal viscosity) | 950 to 1050 | Cs |
Dimethicone 1000 is a high-viscosity silicone fluid with a viscosity of approximately 1000 centistokes, and it is widely used in pharmaceutical and laboratory settings due to its unique properties and versatility.
🏭⚗️ Production
Dimethicone 1000 is synthesized through the polymerization of dimethylsiloxane monomers under controlled conditions, and the resulting polymer is purified to meet the required standards for pharmaceutical and laboratory use. It is typically available as a colorless, odorless liquid with a smooth, non-greasy texture.
🔬 Properties
Dimethicone 1000 exhibits low surface tension, high spreading coefficient, and excellent thermal stability. It is chemically inert, non-toxic, and resistant to oxidation, making it highly suitable for pharmaceutical formulations and laboratory applications. The compound is hydrophobic, forming a protective barrier on surfaces, and it has high gas permeability, allowing for skin respiration and safe use in topical preparations.
🧪 Applications
In pharmaceutical applications, Dimethicone 1000 is used as an anti-foaming agent in oral suspensions, syrups, and topical creams. Its ability to reduce surface tension helps prevent foam formation during manufacturing, ensuring accurate dosing and consistent product quality. Additionally, its lubricating properties are utilized in tablet coatings and ointments to improve ease of application and patient comfort. In laboratory settings, Dimethicone 1000 serves as a lubricant for precision equipment, a mold release agent, and a component in microfluidic devices. Its chemical inertness and stability under varying conditions make it ideal for these sensitive applications.
⚠️ Safety
Dimethicone 1000 is generally considered safe for use in pharmaceutical and laboratory applications when used within recommended concentrations. However, it can be a mild irritant to the skin and eyes, and prolonged or excessive exposure may lead to adverse effects. Appropriate safety measures, including the use of personal protective equipment and proper ventilation, should be observed when handling Dimethicone 1000.
