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Trifluoroacetic Acid is a strong organic acid widely used in organic synthesis and analytical chemistry.

🏭⚗️ Production
Trifluoroacetic acid (TFA) is produced by the electrochemical fluorination of acetic acid or by the oxidation of trifluoroacetaldehyde hydrate. The product is purified by distillation and stored in tightly sealed containers protected from moisture and light.

🔬 Properties
TFA is a colorless, volatile liquid with a pungent odor and strong acidic properties. It is highly soluble in water and most organic solvents. TFA is a strong acid, stronger than acetic acid, and is corrosive to metals and tissue.

🧪 Applications
Trifluoroacetic acid is widely used as a reagent and solvent in peptide synthesis, as a catalyst in organic reactions, and in analytical chemistry for high-performance liquid chromatography (HPLC). It is also used for protein cleavage and deprotection reactions.

⚠️ Safety
Handle with extreme care; trifluoroacetic acid is corrosive and can cause severe burns to skin and eyes. Use gloves, eye protection, and work in a well-ventilated area or fume hood. Avoid inhalation, ingestion, and contact with incompatible materials. Dispose of waste according to local chemical safety regulations.