ان ان دی متیل فرمامید برای سنتز DNA و پپتید
| Formula | C3H7NO |
| Chemical formula | HCON(CH3)2 |
| Density | ~ 0.94 g/cm3 (20°C) |
| Molar mass | 73.10 g/mol |
| CAS number | 68-12-2 |
| HS Code | 29241900 |
| EC number | 200-679-5 |
| Storage | store at +15 to +25 °C |
| SDS | available |
| RTECS | LQ2100000 |
| R phrase | R 61-E20/21-36 |
| S phrase | S 53-45 |
| Odour | weakly amine-like |
| Form | liquid |
| Color | colourless |
| Explosion limit | 2.2 – 16 vol % |
| Ignition temprature | 410 °C |
| Solubility in water | soluble |
| Solubility in ethanol | soluble |
| Solubility in chloroform | soloble(20 ° C) |
| Flash point | 58 °C |
| Melting point | ~-961 °C |
| Boiling point | 153 °C |
| Vapur pressure | 3.77 hPa (20°C) |
| Viscosity dynamical | 0.82 mPa*s (20°C) |
| Purity | ≥ | 99.9 | % |
| Description | Conforms | ||
| Identification | Conforms | ||
| Water | ≤ | 300 | ppm |
| Color | ≤ | 10 | Hazan |
| Acidity | ≤ | 0.0005 | meq/g |
| Alkalinity | ≤ | 0.0002 | meq/g |
| Amines | ≤ | 10.0 | ppm |
| Evaporation residue | ≤ | 10.0 | mg/l |
N,N-Dimethylformamide for DNA & Peptide synthesis is a high-purity, polar aprotic solvent widely used in peptide and oligonucleotide synthesis, as well as in preparative and analytical procedures in pharmaceutical and biochemical laboratories.
🏭⚗️ Production
The solvent is produced by high-purity synthesis and distillation under strictly controlled conditions to remove water and impurities. It is then packaged in sealed, moisture-resistant containers to preserve its chemical integrity and ensure consistent performance in regulated laboratory and industrial environments.
🔬 Properties
N,N-Dimethylformamide is a clear, colorless liquid with a slight amine-like odor. It is highly polar, fully miscible with water and most organic solvents, and chemically stable under normal storage conditions. Its polar aprotic nature allows it to dissolve a wide range of organic and inorganic compounds, making it suitable for reactions requiring strong solvation of ions and polar intermediates.
🧪 Applications
In pharmaceutical and analytical laboratories, N,N-Dimethylformamide is used as a solvent for peptide and oligonucleotide synthesis reactions. It is applied in preparative chromatography, coupling reactions, and dissolution of reagents and intermediates. Additionally, it facilitates laboratory-scale reactions that require high polarity and stability, ensuring reproducible and high-purity results in synthesis and purification workflows.
⚠️ Safety
N,N-Dimethylformamide is toxic, can be absorbed through the skin, and may cause liver damage upon prolonged exposure. It should be handled in a well-ventilated fume hood with gloves, protective eyewear, and lab coats. Containers must be stored tightly sealed in a cool, dry place, away from strong oxidizers and acids. Waste and empty containers should be disposed of according to laboratory hazardous waste regulations.
