استیک اسید HPLC
| Formula | C2H2O2 |
| Chemical formula | CH3COOH |
| Density | 1.05 g/cm3 (20°C) |
| Molar mass | 60.05 g/mol |
| CAS number | 64-19-7 |
| HS Code | 29152100 |
| EC number | 200-580-7 |
| Storage | store at +15 to +25 °C |
| SDS | available |
| RTECS | AF1225000 |
| R phrase | R 10-35 |
| S phrase | S 23.2-26-45 |
| Odour | pungent |
| Form | liquid |
| Color | colourless |
| Explosion limit | 4 to 19.9 vol % |
| Ignition temprature | 485 °C |
| pH value | 2.5 (50 g/l 20 °C) |
| Solubility in water | ( 20 °C)soluble |
| Solubility in ethanol | soluble |
| Flash point | 39 °C |
| Melting point | 17 °C |
| Boiling point | 116 – 118 °C |
| Vapur pressure | 15.4hPa (20°C) |
| Viscosity dynamical | 1.22 mPa*s (20°C) |
| Viscosity kinematic | 1.17 mPa*s (20°C) |
| Saturation Concentration | 38 g/m3 (20°C) |
| Assay | 99.5 to 100.5 | % | |
| Description | Clear | ||
| Solubility | Conforms | ||
| Identification | Conforms | ||
| Color | ≤ | 10 | Hazen |
| Evaporation residue | ≤ | 5.0 | ppm |
| Aluminum | ≤ | 0.02 | ppm |
| Calcium | ≤ | 0.05 | ppm |
| Copper | ≤ | 0.025 | ppm |
| Iron | ≤ | 0.2 | ppm |
| Potassium | ≤ | 0.05 | ppm |
| Magnesium | ≤ | 0.02 | ppm |
| Sodium | ≤ | 0.1 | ppm |
| HPLC gradient suitability test | ≤ | 10 | ppm |
| (220,254 & 280 nm) chromophoric | |||
| impurities on 4-hydroxyacetophenon |
Acetic Acid for HPLC is a high‑purity, analytical‑grade organic acid designed for use in pharmaceutical and analytical laboratories for HPLC mobile phase preparation, pH adjustment, and improving chromatographic resolution.
🏭⚗️ Production
Prepared from ultra‑pure glacial acetic acid under strictly controlled conditions to minimize trace metal and organic contaminants. Standardized for acid concentration, pH, and stability. Supplied in chemically resistant, tightly sealed containers to prevent contamination, moisture uptake, or degradation.
🔬 Properties
A clear, colorless liquid with characteristic pungent odor and acidic properties. Exhibits excellent solubility in water and common organic solvents, minimal UV absorbance suitable for HPLC, and high chemical stability under normal laboratory conditions. Corrosive to metals and tissues; may react with strong bases and oxidizing agents. Store in a cool, dry, well-ventilated area in appropriate containers.
🧪 Applications
Widely used in pharmaceutical and analytical laboratories for preparing HPLC mobile phases, controlling pH, and improving peak shape and reproducibility in reversed-phase chromatography. Supports ion-pairing and gradient elution separations while maintaining low background interference. Solutions and equipment should be handled carefully to maintain analytical-grade purity.
⚠️ Safety
Corrosive; can cause irritation or burns to eyes, skin, and respiratory system. Use in a well-ventilated area with appropriate protective equipment including gloves, goggles, and lab coat. Avoid ingestion and contact with strong oxidizers or bases. Spills should be cleaned up following institutional and environmental safety guidelines. Store in a tightly closed, chemically resistant container in a cool, dry, well-ventilated area away from incompatible substances.




