استونیتریل برای سنتز DNA و پپتید

Acetonitrile for DNA & Peptide Synthesis is a high-purity, synthesis-grade solvent used for DNA and peptide synthesis, as well as purification processes in pharmaceutical and biochemical laboratories.

🏭⚗️ Production
High-purity acetonitrile is produced industrially, often as a by-product of acrylonitrile manufacture, and further purified to reduce water content and remove impurities. For DNA and peptide synthesis, the solvent is processed to extremely low water levels (≤ 30 ppm) to ensure optimal reaction efficiency. The solvent is dispensed into sealed, moisture-resistant containers to maintain stability, prevent contamination, and ensure reproducible results in regulated laboratory environments.

🔬 Properties
Acetonitrile is a clear, colorless, polar aprotic solvent, miscible with water and most organic solvents. It is stable under recommended storage conditions and provides a highly reproducible, low-water environment necessary for sensitive synthetic reactions, such as phosphoramidite coupling in oligonucleotide synthesis or peptide chain elongation in solid-phase peptide synthesis.

🧪 Applications
In pharmaceutical and biochemical laboratories, acetonitrile is used as a solvent for DNA and peptide synthesis, as well as for purification processes such as HPLC. Its low water content and high purity ensure accurate, efficient, and reproducible synthesis of oligonucleotides and peptides. It is also used in method development, routine synthesis, and analytical applications to guarantee reliable and traceable results.

⚠️ Safety
Acetonitrile is highly flammable and toxic. It should be handled following standard laboratory safety protocols, including gloves, protective eyewear, and lab coats. Work in a well-ventilated fume hood. Store in a cool, dry place, protected from heat and ignition sources. Empty containers should be disposed of according to laboratory safety regulations.