Zero oxygen solution
| Storage | With out limitation |
| SDS | available |
| Form | liquid |
| Color | colorless |
| Solubility in water | soluble (20°C) |
| Oxygen | 0± 0.1 | % |
Zero Oxygen Solution is a pharmacopeial-grade reference solution designed for use in pharmaceutical quality control, laboratory calibration, and analytical testing for the removal or measurement of dissolved oxygen in aqueous systems, and for the calibration and performance verification of dissolved oxygen meters and oxygen-sensitive analytical instruments.
🏭⚗️ Production
Prepared under strictly controlled GMP- and pharmacopeial-compliant conditions to ensure precise oxygen scavenging or removal, chemical stability, and minimal contamination. The solution is typically formulated using high-purity oxygen scavengers, reducing agents, or deoxygenated water under inert gas atmospheres. The solution is supplied in chemically resistant, sealed, and light-protected containers to prevent re-oxygenation, contamination, or degradation. Each batch is validated according to USP <1225>, EP 2.2.30, and relevant pharmaceutical testing standards to ensure accuracy, uniformity, and reproducibility.
🔬 Properties
A clear, colorless aqueous solution with dissolved oxygen effectively reduced to near zero levels. Exhibits excellent stability under recommended storage conditions. Minor increases in oxygen content may occur upon prolonged storage or exposure to air; gentle handling under inert conditions restores low oxygen levels without affecting the reference value.
🧪 Applications
Used in pharmaceutical, analytical, and educational laboratories for calibration, validation, and performance testing of dissolved oxygen meters, oxygen sensors, and oxygen-sensitive processes. Suitable for method validation, routine QC analysis, equipment qualification (IQ/OQ/PQ), and compliance with pharmacopeial standards requiring oxygen-free references. Ideal for ensuring accurate measurements in formulation development, bioprocess control, and laboratory research where oxygen-sensitive reactions are involved.
⚠️ Safety
Considered low-hazard but should be handled according to standard laboratory safety practices. Avoid ingestion, inhalation, and direct contact with skin and eyes. Use appropriate personal protective equipment, including gloves, goggles, and a lab coat. Store in tightly sealed, inert-gas-protected containers in a cool, dry environment. Dispose of according to pharmaceutical laboratory waste regulations and environmental safety guidelines.
