Sulfuric acid for HPLC
| Formula: | H2O4S |
| Chemical formula: | H2SO4 |
| Density: | 1.84 g/cm3 (20 °C) |
| Molar mass: | 98.08 g/mol |
| CAS number: | 7664-93-9 |
| EC index number: | 016-020-00-8 |
| HS code: | 28070010 |
| EC number: | 231-639-5 |
| Storage (temperature): | Without limitations. |
| SDS | available |
| RTECS: | WS5600000 |
| R phrase: | R 35 |
| S phrase: | S 26-30-45 |
| Odour: | odourless |
| Form: | liquid |
| Color: | colourless |
| PH value: | 0.3 (49 g/l 25 °C) |
| Solubility in water: | (20˚C) soluble, |
| Solubility in ethanol: | soluble, |
| Boiling point: | ~ 335 °C |
| Melting point: | ~ 3 °C |
| Vapour pressure: | ~ 0.0001 hpa (20°C) |
| Thermal decomposition: | ~ 338°C |
Sulfuric Acid for HPLC is a high‑purity, analytical‑grade reagent used in pharmaceutical and analytical laboratories for HPLC mobile phase preparation, pH adjustment, and controlled chemical reactions.
🏭⚗️ Production
Prepared from ultra‑pure sulfuric acid under strictly controlled conditions to minimize trace metals, water content, and other contaminants. Standardized for concentration, density, and chemical stability. Supplied in chemically resistant, tightly sealed containers to prevent contamination, moisture uptake, or degradation.
🔬 Properties
A colorless to slightly yellow, oily liquid with a sharp, pungent odor. Strongly acidic, highly hygroscopic, and highly corrosive. Chemically stable under controlled laboratory conditions but reacts violently with water, organic materials, and bases. Corrosive to metals and tissues. Store in a cool, dry, well‑ventilated area in containers resistant to strong acids.
🧪 Applications
Used in pharmaceutical and analytical laboratories for preparing HPLC mobile phases, pH adjustment in aqueous and mixed solvent systems, and supporting controlled chemical reactions. Maintains reproducibility and analytical-grade purity in chromatographic separations. Solutions and equipment should be handled carefully to preserve purity.
⚠️ Safety
Corrosive and highly irritating; can cause severe burns to eyes, skin, and respiratory tract. Highly reactive with organics, bases, and water. Use in a well‑ventilated area with appropriate protective equipment including gloves, goggles, and lab coat. Avoid ingestion and contact with incompatible substances. Spills should be neutralized and cleaned up according to institutional and environmental safety guidelines. Store in a tightly closed, chemically resistant container in a cool, dry, well‑ventilated area away from incompatible materials.
