Potassium tertbutoxide

Potassium tert-Butoxide is a strong, non-nucleophilic base commonly used in organic synthesis and chemical research.

🏭⚗️ Production
Potassium tert-butoxide is produced by the reaction of potassium metal with tert-butanol under anhydrous conditions. The reaction mixture is purified by distillation or recrystallization, yielding a white to pale yellow solid, which is stored in airtight containers under inert atmosphere to prevent degradation by moisture and air.

🔬 Properties
Potassium tert-butoxide appears as a white to pale yellow crystalline powder. It is highly reactive, strongly basic, and soluble in organic solvents like tetrahydrofuran and ethers. It is moisture sensitive and decomposes upon contact with water, releasing flammable gases.

🧪 Applications
This compound is widely used as a strong base in organic synthesis for elimination reactions, deprotonation, and as a catalyst in various chemical transformations including synthesis of alkenes and substituted compounds.

⚠️ Safety
Handle with extreme care; potassium tert-butoxide is highly reactive and corrosive. It reacts violently with water and moisture, releasing flammable gases. Use gloves, eye protection, and work under inert atmosphere in a well-ventilated area. Avoid inhalation, ingestion, and skin contact. Store away from moisture and incompatible substances. Dispose of waste according to local chemical safety regulations.