Potassium chloride for HPLC
| Formula | ClK |
| Chemical formula | KCl |
| Density | 1.98 g/cm3 (20°C) |
| Molar mass | 74.55 g/mol |
| CAS number | 7447-40-7 |
| HS Code | 31042090 |
| EC number | 231-211-8 |
| Storage | without limitations |
| SDS | available |
| RTECS | TS8050000 |
| Odour | oderless |
| Form | solid |
| Color | white |
| p H | 5.5 – 8.0 (50g/l 20°C ) |
| Solubility in water | 347 g/l (20°C) |
| Solubility in ethanol | almost insluble (20°C) |
| Boiling point | 1413 °C |
| Melting point | 773 °C |
| Vapour pressure | low |
| Assay | 99.0 – 100.5 | % | |
| Description | Conforms | ||
| Solubility | Conforms | ||
| Clarity & color of solution | Conforms | ||
| Identification | Conforms | ||
| Insoluble matter | ≤ | 0/005 | % |
| Aluminum | ≤ | 0/05 | ppm |
| Calcium | ≤ | 20 | ppm |
| Copper | ≤ | 2 | ppm |
| Iron | ≤ | 1 | ppm |
| Sodium | ≤ | 50 | ppm |
| Magnesium | ≤ | 10 | ppm |
| HPLC gradient suitability test (220,254 | ≤ | 10 | ppm |
| & 280 nm) chromophoric impurities | |||
| on 4-hydroxyacetophenon |
Potassium Chloride for HPLC is a pharmacopeial-grade reagent formulated for pharmaceutical, analytical, and laboratory applications requiring precise ionic strength control and reproducible chromatographic performance.
🏭⚗️ Production
Manufactured under GMP- and pharmacopeial-compliant conditions using high-purity potassium chloride (HPLC or analytical grade). Supplied as a crystalline solid or pre-dissolved solution suitable for preparation of buffer systems, mobile phases, and ionic strength adjustment in pharmaceutical and research laboratories. Produced in controlled environments to prevent contamination from ions, particulates, or organic matter. Packaged in chemically resistant, airtight containers to ensure stability and prevent moisture uptake. Each batch is validated according to USP and HPLC standards to guarantee purity, consistency, and reliability for analytical applications.
🔬 Properties
A high-purity, white crystalline solid with excellent solubility in water and stable chemical characteristics. Forms clear, colorless solutions suitable for use in pharmaceutical analysis and HPLC applications. Hygroscopic under high humidity, but minor clumping does not affect performance and can be corrected by gentle mixing or dissolution.
🧪 Applications
Used in preparation of mobile phases, buffer systems, and for ionic strength adjustment in pharmaceutical and research laboratories. Essential for HPLC, QC analysis, method development, and formulation studies where precise ionic composition is required. Ensures reproducibility in chromatographic separation and drug analysis procedures.
⚠️ Safety
May cause irritation to eyes, skin, or respiratory tract. Avoid ingestion and inhalation. Use appropriate personal protective equipment, including gloves, goggles, and lab coat. Store in tightly sealed containers in a cool, dry environment to prevent moisture absorption. Dispose of according to laboratory, pharmacopeial, and environmental regulations.




