Phenoxy ethanol

Phenoxyethanol is an aromatic ether-alcohol with the chemical formula C₈H₁₀O₂. It is widely used in pharmaceutical and laboratory settings due to its preservative properties, chemical stability, and compatibility with various formulations.

🏭⚗️ Production
Phenoxyethanol is synthesized through the reaction of phenol with ethylene oxide. The resulting product is purified to meet the required standards for pharmaceutical and laboratory use. It is typically available as a colorless, slightly viscous liquid with a faint rose-like odor.

🔬 Properties
Phenoxyethanol is slightly soluble in water but miscible with ethanol, acetone, and glycerol. It exhibits broad-spectrum antimicrobial activity, effective against both Gram-positive and Gram-negative bacteria, as well as yeasts. The compound is chemically stable and maintains its efficacy across a wide pH range (approximately 3–10). It has a boiling point of 245°C and a density of 1.107 g/cm³ at 20°C.

🧪 Applications
In pharmaceuticals, phenoxyethanol is commonly used as a preservative in injectable solutions, vaccines, and ophthalmic preparations. It helps prevent microbial contamination and extends the shelf life of these products. In laboratory settings, phenoxyethanol serves as a preservative in biological samples and reagents, ensuring the integrity of specimens during storage and transport. It is also utilized in the formulation of various cosmetic products for its antimicrobial properties.

⚠️ Safety
Phenoxyethanol is generally considered safe for use in pharmaceuticals and laboratory applications when used within recommended concentrations. However, it can be a mild irritant to the skin and eyes. Prolonged or excessive exposure may lead to adverse effects. Therefore, appropriate safety measures, including the use of personal protective equipment and proper ventilation, should be observed when handling phenoxyethanol.