Methanol for gradient HPLC
| Formula: | CH4O |
| Chemical formula: | CH3OH |
| Density: | 0.79 g/cm3 (20 °C) |
| Molar mass: | 32.04 g/mol |
| CAS number: | 67-56-1 |
| EC index number: | 603-001-00-X |
| HS code: | 29051100 |
| EC number: | 200-659-6 |
| Storage (temperature): | Without limitationavailable |
| SDS | PC1400000 |
| RTECS: | R |
| R phrase: | 11-23/24/25-39/23/24/2 |
| S phrase: | 5 |
| Odour: | S 7-16-36/37-45 |
| Form: | characteristic |
| Color: | liquid |
| Explosion limit: | colourless |
| Ignition temperature: | 5.5 -36.5 Vol % |
| Solubility in water: | 455 °C (DIN 51794) |
| Flash point: | (20°C) soluble |
| Boiling point: | 11 °C (c.c.) |
| Melting point: | 64.5 °C (1013 hPa) |
| Vapour pressure: | -98 °C |
| Viscosity dynamical : | 128 hPa (20 °C) |
| Saturation | 0.597 mPa*s (20 °C) |
| concentration (air): | 166 g/m3 (20 °C) |
| Assay | ≥ | 99.9 | % |
| Solubility | Conforms | ||
| Color & Description | Conforms | ||
| Identification | Conforms | ||
| Alkalinity | ≤ | 3.0 | ppm |
| Acidity | ≤ | 0.45 | ml |
| Acetone & aldehyde | Conforms | ||
| Residue on evaporation | ≤ | 3.0 | mg/l |
| Transmission at 220nm | ≤ | 55 | % |
| Transmission at 235nm | ≤ | 83 | % |
| Transmission from 260nm | ≤ | 98 | % |
| Absorbance at 235nm | ≤ | 2.0 | mAU |
| Absorbance at 254nm | ≤ | 1.0 | mAU |
| Absorbance at 225nm | ≤ | 0.17 | mAU |
| Water | ≤ | 0.03 | % |
| Filtered by 0.2 μm suitable filter |
Methanol for Gradient HPLC is a high‑purity solvent specifically formulated for gradient chromatographic applications, ensuring low UV background, stable retention times, and reliable reproducibility across variable mobile-phase compositions.
🏭⚗️ Production
Purified through multi-stage distillation to remove metals, water, and organic impurities. Quality-controlled for low UV absorbance, conductivity, and minimal background interference. Packaged in airtight, solvent-resistant containers to prevent contamination, moisture uptake, and degradation during storage.
🔬 Properties
A clear, colorless, highly volatile liquid with a mild alcohol odor. Fully miscible with water and most organic solvents. Offers low viscosity, high purity, and excellent UV transparency. Hygroscopic; store tightly sealed in cool, dry conditions away from light.
🧪 Applications
Used as the primary mobile-phase solvent in gradient HPLC methods, sample preparation, and standard dilutions. Provides smooth baseline transitions, reproducible peak shapes, and consistent chromatographic performance in routine and complex gradient analyses.
⚠️ Safety
Highly flammable and harmful if inhaled, ingested, or absorbed through skin. Vapors may irritate eyes and respiratory tract. Use appropriate PPE and work in a ventilated area or fume hood. Keep away from heat, sparks, and oxidizers. Store in tightly closed, compatible containers.
