Glycerin Polyethylene Glycol Ether
| CAS number | 31694-55-0 |
| HS Code | 34021300 |
| Storage | Storage at 5 to 30 ◦C |
| SDS | available |
| Appearance | Conforms | ||
| Solubility | Conforms | ||
| Viscosity @ 98.9 | ~ | 11.0 | Cst |
| Hydroxyl value | 400.0 to 430.0 | ||
| Spesific gravity | ~ | 1.13 | |
| Average molecular weight | 390.0 to 420.0 | ||
| Water | ≤ | 1.0 | % |
| pH | 5.0 to 7.0 |
Glycerin Polyethylene Glycol Ether is a non-ionic surfactant and emulsifier synthesized by the ethoxylation of glycerin with polyethylene glycol. It appears as a clear to slightly hazy, odorless or nearly odorless liquid and is widely used in pharmaceutical and laboratory formulations for its emulsifying, solubilizing, and stabilizing properties.
🏭⚗️ Production
Glycerin Polyethylene Glycol Ether is produced by reacting glycerin with ethylene oxide under controlled conditions, resulting in a polyethylene glycol ether derivative. This process yields a mixture of polyethylene glycol ethers that are liquid at room temperature, making them suitable for various pharmaceutical and laboratory applications.
🔬 Properties
Glycerin Polyethylene Glycol Ether is soluble in both water and alcohol, has a low viscosity, and is chemically stable. The substance exhibits excellent emulsifying and solubilizing properties, making it effective in enhancing the bioavailability of poorly soluble drugs and active ingredients. It also acts as a stabilizer in emulsions and can function as a co-emulsifier in oil-in-water systems.
🧪 Applications
In pharmaceutical formulations, Glycerin Polyethylene Glycol Ether serves as a carrier for fat-soluble vitamins (A, D, E, K), herbal extracts, and sensitive active pharmaceutical ingredients (APIs). It is used in oral formulations such as softgel capsules, syrups, and dietary supplements. Additionally, it is employed in topical applications like creams, ointments, and gels, and can be used in certain injectable formulations.
In laboratory settings, Glycerin Polyethylene Glycol Ether is utilized as a solubilizing agent to improve the dissolution of hydrophobic compounds in aqueous solutions. It also serves as a stabilizer in emulsions and as a carrier in drug delivery systems.
⚠️ Safety
Glycerin Polyethylene Glycol Ether is generally recognized as safe for topical and oral use in recommended concentrations. It is non-toxic, non-irritating, and hypoallergenic for most individuals. However, rare allergic reactions may occur in individuals sensitive to glycerin or polyethylene glycol derivatives. Standard handling procedures, including proper storage and hygiene, should be followed to ensure safety during pharmaceutical or laboratory use.
