Dimethicone100
| CAS number | 7631-86-9 |
| HS Code | 39100090 |
| Storage | Storage at 5 to 30 °C |
| SDS | available |
| Appearance | Conforms | ||
| Identification | Conforms | ||
| Solubility | Conforms | ||
| Specific gravity | 0.962 to 0.970 | ||
| Viscosity | 95.0 to 105.0 | Cs | |
| Refractive index | 1.4005 to 1.4045 | ||
| Loss on heating | ≤ | 0.3 | % |
| Heavy metals | ≤ | 0.0005 | % |
| Acidity | ≤ | 0.1 | ml |
| Assay (nominal viscosity) | 95.0 to 105.0 | Cs |
Dimethicone 100 is a linear, non-reactive polydimethylsiloxane fluid with a viscosity of approximately 100 centistokes. It is widely used in pharmaceutical and laboratory settings due to its unique properties and versatility.
🏭⚗️ Production
Dimethicone 100 is synthesized through the polymerization of dimethylsiloxane monomers under controlled conditions. The resulting polymer is purified to meet the required standards for pharmaceutical and laboratory use. It is typically available as a colorless, odorless liquid with a smooth, non-greasy texture.
🔬 Properties
Dimethicone 100 exhibits low surface tension, high spreading coefficient, and excellent thermal stability. It is chemically inert, non-toxic, and resistant to oxidation, making it suitable for various applications. The compound is hydrophobic, forming a protective barrier on surfaces, and has a high permeability to gases, allowing for the respiration of the skin.
🧪 Applications
In pharmaceuticals, Dimethicone 100 is used as an anti-foaming agent in oral suspensions, syrups, and topical creams. Its ability to reduce surface tension helps prevent the formation of foam during manufacturing processes, ensuring accurate dosing and product consistency. Additionally, its lubricating properties make it useful in tablet coatings and ointments, enhancing ease of application and patient comfort.
In laboratory settings, Dimethicone 100 serves as a lubricant for equipment, a mold release agent, and a component in microfluidic devices. Its chemical inertness and stability under varying conditions make it ideal for these applications.
⚠️ Safety
Dimethicone 100 is generally considered safe for use in pharmaceutical and laboratory applications when used within recommended concentrations. However, it can cause mild irritation in sensitive individuals. Proper handling procedures should be followed, including the use of personal protective equipment such as gloves and goggles. The compound should be stored in a cool, dry place away from incompatible materials to maintain its stability and ensure safe use.
