Acetonitrile for gradient HPLC
| Formula | C2H3N |
| Chemical formula | C2H3N |
| Density | 0.786 g/cm3 (20°C) |
| Molar mass | 41.05 g/mol |
| EC index number | 608-001-00-3 |
| CAS number | 75-05-8 |
| HS Code | 29269095 |
| EC number | 200-835-2 |
| Storage | 5°C to +25°C |
| SDS | available |
| RTECS | AL77000000 |
| R phrase | R 11-20/21/22-36 |
| S phrase | S 16-36/37 |
| Odour | ether like |
| Form | liquid |
| Color | Colourless |
| Explosion limit | 3.0 – 17 vol % |
| Ignation temperature | 524°C |
| Solubility in water | Soluble (20°C) |
| Solubility in ethanol | miscible |
| Solubility in chloroform | miscible |
| Flash point | 2 °C |
| Boiling point | 81.6 °c (1013 hpa ) |
| Melting point | – 45.7 °C |
| Vapour pressure | 97 hpa (20°C) |
| Viscosity dynamical | 0.316 mpa*s (25°C) |
| Saturation concentration | 163 g/m3 (20°C) |
| Assay | ≤ | 99 | % |
| Description | Conforms | ||
| Solubility | Conforms | ||
| Identification | Conforms | ||
| Acidity | ≤ | 0/00016 | % |
| Density | 0.782 – 0.783 | g/cm3 | |
| Evaporation residue | ≤ | 0/005 | % |
| Water | ≤ | 0/1 | % |
| Transmission at 195 nm | ≥ | 60 | % |
| Transmission at 200 nm | ≥ | 80 | % |
| Transmission at 240 nm | ≥ | 98 | % |
| Filtered by 0.2 μm suitable filter | 0/2 |
Acetonitrile for Gradient HPLC is a high-purity solvent optimized for gradient elution, providing low UV background, excellent baseline stability, and reliable chromatographic performance.
🏭⚗️ Production
Refined through multi-stage distillation to remove water, metals, and organic contaminants. QC-tested for low UV absorbance and stable gradient behavior. Packaged in airtight, solvent-resistant containers to prevent moisture uptake and impurity introduction.
🔬 Properties
A clear, colorless, highly volatile liquid with a mild odor. Fully miscible with water and common organic solvents. Offers low viscosity, rapid mixing, and consistent UV transparency—ideal for gradient HPLC. Hygroscopic; store tightly sealed in cool, dry conditions.
🧪 Applications
Used extensively in gradient HPLC for improved resolution, reproducibility, and peak symmetry. Suitable for analytes across a wide polarity range. Also used in sample preparation and dilution where high-purity organic solvents are required.
⚠️ Safety
Highly flammable and harmful if inhaled, ingested, or absorbed through the skin. May irritate eyes and respiratory tract. Use PPE and adequate ventilation or a fume hood. Keep away from heat, sparks, and oxidizing agents. Store in tightly closed, compatible containers.
