Sodium Hydroxide solution 27%
| Density | 1.30g/cm3 (20°C) |
| HS Code | 28151200 |
| Storage | Storage at +15 to +25 °C |
| SDS | available |
| R phrase | R 35 |
| S phrase | S 26-36/37/39-45 |
| Odour | odourless |
| Form | liquid |
| Color | colourless to slightly yellowish |
| Solubility in water | soluble (20°C) |
| Melting point | 9°C |
| Vapour pressure | ~8h Pa |
| Viscosity dynamical | 19 mPa*s |
| Assay | ≥ | 27.0 | % |
| Description | Conforms | ||
| Identification | Conforms | ||
| Solubility | Conforms | ||
| Carbonate | ≤ | 0.1 | % |
| Chloride | ≤ | 0.0005 | % |
| Phosphate | ≤ | 0.0005 | % |
| Silicate | ≤ | 0.001 | % |
| Sulphate | ≤ | 0.0005 | % |
| Total nitrogen | ≤ | 0.0001 | % |
| Heavy metals | ≤ | 0.0005 | % |
| Aluminium | ≤ | 0.0005 | % |
| Iron | ≤ | 0.0005 | % |
Sodium Hydroxide Solution 27% is an aqueous alkaline solution commonly used in pharmaceutical manufacturing and laboratory applications for its strong pH‑regulating, neutralizing, and cleaning properties.
🏭⚗️ Production
Sodium Hydroxide (NaOH) is industrially produced through the chlor‑alkali process, which involves the electrolysis of sodium chloride brine to generate NaOH, chlorine, and hydrogen. The 27% solution is prepared by carefully diluting concentrated NaOH with purified water under controlled conditions, ensuring a stable and high-purity alkaline solution suitable for pharmaceutical and laboratory use.
🔬 Properties
Sodium Hydroxide Solution 27% is highly alkaline and completely miscible with water. It reacts vigorously with acids to produce salts and water and releases heat upon dilution. The solution is chemically stable when stored in sealed, corrosion-resistant containers, protected from atmospheric carbon dioxide, which can slowly form sodium carbonate.
🧪 Applications
In pharmaceutical formulations, Sodium Hydroxide Solution 27% is used as a pH-adjusting agent, neutralizing agent, and process reagent in the synthesis, purification, and formulation of drugs. It is particularly important for maintaining precise pH in ophthalmic solutions, sterile injectables, and multi-dose formulations.
In laboratory settings, it serves as a standard titrant, cleaning and degreasing agent, and neutralizer of acidic residues. It is widely used in analytical chemistry, microbiological preparations, and other experiments requiring strong alkaline conditions.
⚠️ Safety
Sodium Hydroxide Solution 27% is corrosive and can cause severe burns on contact with skin or eyes. It must be handled with protective gloves, goggles, and lab coats. The solution should be stored in tightly closed, corrosion-resistant containers, away from acids, oxidizers, and moisture. Proper spill response and neutralization procedures are essential in pharmaceutical and laboratory environments.
