Cetearath 20

Ceteareth-20 is a non-ionic emulsifier composed of ethoxylated cetearyl alcohol, containing approximately 20 ethylene oxide units. It appears as a white to off-white waxy solid and is widely used in pharmaceutical and laboratory formulations for its emulsifying, stabilizing, and solubilizing properties.

🏭⚗️ Production
Ceteareth-20 is synthesized by ethoxylating cetearyl alcohol with ethylene oxide, resulting in a mixture with an average of 20 ethylene oxide units. This process imparts the emulsifier with its characteristic properties, making it suitable for various pharmaceutical and laboratory applications.

🔬 Properties
Ceteareth-20 has an HLB (Hydrophilic-Lipophilic Balance) value of approximately 15.7, indicating its suitability for oil-in-water emulsions. It is soluble in water and ethanol, has a melting point between 45–50°C, and a cloud point between 90–95°C. The substance is chemically stable and exhibits good compatibility with other ingredients, including electrolytes and hard water.

🧪 Applications
In pharmaceutical formulations, Ceteareth-20 serves as an emulsifier and stabilizer in creams, ointments, and lotions, ensuring uniform dispersion of active ingredients and enhancing product stability. It also functions as a solubilizing agent for poorly soluble compounds. In laboratory settings, Ceteareth-20 is utilized in the preparation of emulsions and as a component in the formulation of controlled-release drug delivery systems.

⚠️ Safety
Ceteareth-20 is generally recognized as safe for topical use. It is non-toxic, non-irritating, and hypoallergenic in recommended concentrations. However, rare allergic reactions may occur in sensitive individuals. Standard handling procedures, including proper storage and hygiene, should be followed to ensure safety during pharmaceutical or laboratory use.