PEG-150 Distearate
| CAS number | 08/07/9005 |
| HS Code | 29181990 |
| Storage | Storage at 5 to 30 °C |
| SDS | available |
| Appearance | Conforms | ||
| Solubility | Conforms | ||
| Saponification value | 14.0 to 28.0 | ||
| Acid value | ≤ | 10.0 | |
| HLB | ~ | 18.9 | |
| Melting point | 50.0 to 60.0 | °C | |
| Water | ≤ | 3.0 | % |
| pH | 4.5 to 7.5 |
PEG-150 Distearate is a water-soluble, high-molecular-weight polyethylene glycol derivative widely used in pharmaceutical and laboratory formulations due to its emulsifying and solubilizing properties.
🏭⚗️ Production
PEG-150 Distearate is synthesized by the esterification of stearic acid with polyethylene glycol 150 under controlled conditions, followed by purification to meet pharmaceutical and laboratory-grade standards. It is typically a white, waxy solid or granular substance with good dispersibility in water.
🔬 Properties
PEG-150 Distearate exhibits excellent emulsifying properties, allowing it to stabilize oil-in-water formulations. It is chemically inert, non-toxic, and highly soluble in aqueous systems. The compound also has good thermal stability and compatibility with a wide range of pharmaceutical excipients, making it suitable for diverse formulations.
🧪 Applications
In pharmaceutical applications, PEG-150 Distearate is primarily used as an emulsifying agent in creams, ointments, and topical gels. Its ability to stabilize emulsions ensures uniform distribution of active ingredients and improves the texture and consistency of formulations. In laboratory settings, PEG-150 Distearate can be used as a solubilizer or dispersing agent in aqueous solutions, as well as a component in drug delivery research to improve the solubility and bioavailability of hydrophobic compounds.
⚠️ Safety
PEG-150 Distearate is generally regarded as safe for pharmaceutical and laboratory use when applied within recommended concentrations. It may cause mild irritation upon prolonged contact with skin or eyes, so proper safety precautions, including the use of gloves and eye protection, are recommended when handling this compound.
