Octyldodecanol

Octyldodecanol is a branched-chain fatty alcohol widely used in pharmaceutical and laboratory applications for its emollient, solubilizing, and emulsifying properties. It appears as a clear, colorless to slightly yellow oily liquid with a mild odor and is insoluble in water but soluble in organic solvents.

🏭⚗️ Production
Octyldodecanol is synthesized through the Guerbet condensation of octanol and dodecanol, resulting in a high-purity product suitable for pharmaceutical and laboratory applications.

🔬 Properties
Octyldodecanol is a clear, colorless to slightly yellow oily liquid with a mild odor. It is insoluble in water but soluble in organic solvents and exhibits excellent emollient, solubilizing, and emulsifying properties. The compound maintains its effectiveness under recommended storage conditions and is chemically stable.

🧪 Applications
In pharmaceutical formulations, Octyldodecanol is used as an emollient and solubilizer in topical creams, lotions, and ointments. It serves as a carrier for lipophilic drugs, enhancing their solubility and stability in aqueous formulations. Additionally, Octyldodecanol is utilized in the preparation of oil-in-water microemulsions for dermal drug delivery systems. In laboratory settings, it is employed as a solvent and emulsifying agent in various analytical and experimental procedures.

⚠️ Safety
Octyldodecanol is generally regarded as non-toxic and non-irritant at the levels employed as an excipient in pharmaceutical and laboratory applications. However, it should be handled with care to avoid inhalation of vapors or prolonged skin contact. Appropriate personal protective equipment, including gloves and goggles, should be worn during handling. The compound should be stored in tightly sealed containers, away from excessive heat or sunlight, in a cool, dry, and well-ventilated area to maintain its stability and effectiveness.