Niacinamide (vitamin B3)
| Molecular Formula | C6H6N2O |
| Molecular Weight | 122.127 g/mol |
| CAS number | 98-92-0 |
| HS Code | 29362920 |
| Storage | Storage at 5 to 30 °C |
| SDS | available |
| Appearance | Conforms | ||
| Identification | Conforms | ||
| Solubility | Conforms | ||
| Melting range | 128.0 to 131.0 | °c | |
| Readily carbonizable substances | Conforms | ||
| Residue on ignition | ≤ | 0.1 | % |
| Heavy metals | ≤ | 0.003 | % |
| Loss on drying | ≤ | 0.5 | % |
| Assay | 98.5 to 101.5 | % |
Niacinamide (Vitamin B3) is a water-soluble vitamin belonging to the B group, chemically known as nicotinamide. It appears as a white crystalline powder and is widely used in pharmaceutical and laboratory formulations for its essential role in energy metabolism and its therapeutic properties.
🏭⚗️ Production
Niacinamide is synthesized through the hydrolysis of nicotinic acid (niacin) or by the reduction of nicotinic acid derivatives. The production process ensures high purity and compliance with pharmaceutical standards, making it suitable for various applications in medicine and laboratory settings.
🔬 Properties
Niacinamide has a molecular formula of C₆H₆N₂O and a molecular weight of 122.12 g/mol. It is highly soluble in water and ethanol, with a melting point between 128–131°C. The substance is chemically stable and exhibits low toxicity, making it safe for use in pharmaceutical and laboratory applications.
🧪 Applications
In pharmaceutical formulations, Niacinamide is utilized in the treatment of conditions such as pellagra, hyperlipidemia, and as a component in multivitamin supplements. It is also employed in laboratory settings for its role in cellular metabolism studies and as a precursor in the synthesis of coenzymes NAD and NADP.
⚠️ Safety
Niacinamide is generally recognized as safe for use in pharmaceutical and laboratory applications. However, as with any compound, proper handling and adherence to safety protocols are essential to ensure safe usage.
