محلول بریج 35

Brij 35 Solution is a water-based solution of Brij 35, a non-ionic surfactant used extensively in biochemistry, molecular biology, and various industrial applications. It is commonly used as a detergent in laboratory settings to stabilize proteins, solubilize lipids, and aid in the disruption of cell membranes.

🏭⚗️ Production
Brij 35 Solution is typically prepared by dissolving Brij 35 (polyoxyethylene ether of tetradecanol) in water. The solution is available in various concentrations, depending on the specific application. The preparation involves mixing the powdered or liquid form of Brij 35 with distilled water or buffer solutions to achieve the desired concentration.

🔬 Properties
Brij 35 Solution is characterized by its clear, stable appearance when dissolved in water. The solution is highly effective at maintaining solubility of hydrophobic molecules in aqueous environments. It has a hydrophilic-lipophilic balance (HLB) of around 16.9, making it particularly useful for stabilizing membrane proteins, lipids, and other hydrophobic compounds. Brij 35 is soluble in both water and organic solvents, and its solutions are stable across a range of pH levels and temperatures.

🧪 Applications
• Protein solubilization: Commonly used in protein extraction and solubilization, particularly for membrane-bound proteins.
• Cell membrane disruption: Employed in experiments requiring cell lysis or membrane disruption for the extraction of cellular components like proteins and lipids.
• Electrophoresis: Used in gel electrophoresis buffers to help solubilize hydrophobic proteins and nucleic acids.
• Pharmaceutical industry: Used in drug delivery systems to enhance the solubility of hydrophobic drugs.
• Cosmetics and personal care: Incorporated into formulations such as creams and lotions as an emulsifying agent.