Buffer PH 12
| Density: | 1.002 g/cm3 |
| HS code: | 38220000 |
| Storage | Without limilations. |
| SDS | not required |
| Form: | liquid |
| pH-Value @ 25°C | 12.00 ± 0.05% |
Buffer pH 12 is a pharmacopeial-grade reference solution designed for use in pharmaceutical quality control, laboratory calibration, and analytical testing for the calibration and performance verification of pH meters, electrodes, and other pH-sensitive analytical instruments.
🏭⚗️ Production
Prepared under strictly controlled GMP- and pharmacopeial-compliant conditions to ensure precise pH, chemical stability, and minimal contamination. The pH 12 value is achieved using high-purity alkaline salts (commonly sodium hydroxide or borate-based compounds) dissolved in deionized water, providing a stable and reproducible alkaline reference. The solution is supplied in chemically resistant, sealed, and light-protected containers to prevent contamination, CO₂ absorption, or degradation. Each batch is validated according to USP <791>, EP 2.2.3, and relevant pharmaceutical testing standards to ensure accuracy, uniformity, and reproducibility.
🔬 Properties
A clear, colorless to slightly bluish aqueous solution with a defined pH of 12 at 25 °C. Exhibits excellent stability under recommended storage conditions. Minor changes in pH may occur upon prolonged exposure to air or light; gentle mixing restores homogeneity without affecting the reference value.
🧪 Applications
Used in pharmaceutical, analytical, and educational laboratories for calibration, validation, and performance testing of pH meters, electrodes, and other pH-sensitive instruments. Suitable for method validation, routine QC analysis, equipment qualification (IQ/OQ/PQ), and compliance with pharmacopeial standards requiring high-pH references. Ideal for ensuring accurate measurements in formulation development, process control, and laboratory research.
⚠️ Safety
Considered corrosive and should be handled according to standard laboratory safety practices. Avoid ingestion, inhalation, and direct contact with skin and eyes. Use appropriate personal protective equipment, including gloves, goggles, and a lab coat. Store in tightly sealed, light-protected containers in a cool, dry environment. Dispose of according to pharmaceutical laboratory waste regulations and environmental safety guidelines.
