Water with 0.1% trifluoracetic acid for HPLC

Water with 0.1% Trifluoroacetic Acid (TFA) for HPLC is a high‑purity, analytical‑grade aqueous solution prepared for use in pharmaceutical and analytical laboratories for HPLC mobile phase preparation, pH adjustment, and improving chromatographic resolution.

🏭⚗️ Production
Prepared by dissolving ultra-pure trifluoroacetic acid in HPLC‑grade water under rigorously controlled conditions to minimize trace metal and organic contaminants. Standardized for acid concentration, pH, and solution stability. Supplied in chemically resistant, tightly sealed containers to prevent contamination, moisture uptake, or degradation.

🔬 Properties
A clear, colorless liquid with strong acidic properties. Provides low pH (~2) suitable for reversed-phase HPLC, minimal UV absorption at common detection wavelengths, and high chemical stability under normal storage conditions. Corrosive to metals and tissues; reacts with strong bases and certain organics. Store in a cool, dry, well‑ventilated area in appropriate containers.

🧪 Applications
Widely used in pharmaceutical and analytical laboratories for preparing HPLC mobile phases, controlling pH, and improving peak shape and reproducibility in peptide, protein, and small molecule analyses. Enhances ion-pairing and reversed-phase separations while maintaining low background interference. Solutions and equipment should be handled carefully to preserve analytical-grade purity.

⚠️ Safety
Corrosive; can cause severe irritation or burns to eyes, skin, and respiratory tract. Use in a well-ventilated area with appropriate protective equipment including gloves, goggles, and lab coat. Avoid ingestion and contact with metals, bases, or oxidizers. Spills must be neutralized and cleaned up following institutional and environmental safety guidelines. Store in a tightly closed, chemically resistant container in a cool, dry, well-ventilated area away from incompatible substances.