Diethylene glycol
| Chemical formula | C4H10O3 |
| Density | 1.1184 g/cm3 |
| Molar mass | 106.12g/mol |
| HS Code | 29094100 |
| CAS number | 111-46-6 |
| Storage | Store at +15 to +25°C |
| EC number | 203-872-2 |
| SDS | available |
| RTECS | ID5950000 |
| R phrase | R 22 |
| S phrase | S 46 |
| Odour | oduorless |
| Form | liquid |
| Color | colourless |
| Explosion limit | 0.7 – 22 vol % |
| Ignition temprature | 345 C |
| p H value | 6.0 – 8.0 (200 g/l 20°C) |
| Solubility in water | freely soluble (20°C) |
| Solubility in ethanol | soluble (25°C) |
| Flash point | 140 C |
| Boiling point | 242 to 247 °C |
| Melting point | ~-10 C |
| Vapour pressure | ~0.03 hPa |
| Viscosity dynamical | 36.8 mPa*S |
| Saturation concentration | 0.12 g/m3 |
| Assay | ≥ | 99.0 | % |
| Description | Conforms | ||
| Identification | Conforms | ||
| Density | 1.115 – 1.117 | ||
| Water (K.F) | ≤ | 0.30 | % |
Diethylene Glycol (DEG) is a colorless, odorless, and hygroscopic liquid with a sweet taste. It is commonly used in pharmaceutical and laboratory applications due to its solvent properties and chemical stability.
🏭⚗️ Production
Diethylene glycol is produced through the hydration of ethylene oxide, resulting in a mixture of mono-, di-, and triethylene glycols. The diethylene glycol fraction is separated and purified for use in various applications.
🔬 Properties
DEG is miscible with water, alcohols, ethers, and acetone. It has a boiling point of approximately 245°C and a melting point around -10°C. The substance is hygroscopic and can absorb moisture from the air, which may affect its concentration and properties over time.
🧪 Applications
In pharmaceutical formulations, DEG serves as a solvent for active pharmaceutical ingredients and excipients. It is utilized in the preparation of oral and topical dosage forms, ensuring the solubility and stability of the active compounds.
In laboratory settings, DEG is employed as a solvent in various analytical procedures, including chromatography and spectroscopy. Its ability to dissolve a wide range of substances makes it valuable in sample preparation and reagent formulation.
⚠️ Safety
Diethylene glycol is considered toxic and can cause serious health effects if ingested, inhaled, or absorbed through the skin. Symptoms of exposure may include headache, dizziness, nausea, and in severe cases, kidney and nervous system damage. Proper handling procedures, including the use of personal protective equipment and adequate ventilation, are essential when working with DEG. It is crucial to adhere to safety guidelines and regulatory standards to minimize exposure risks.
